Search result: Catalogue data in Spring Semester 2019
Chemistry Bachelor  | ||||||
 Bachelor Studies (Programme Regulations 2018) | ||||||
| 2. Semester | ||||||
| Compulsory Subjects First Year Examinations | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|---|
| 529-0012-02L | General Chemistry (Inorganic Chemistry) II | O | 4 credits | 3V + 1U | H. Grützmacher, W. Uhlig | |
| Abstract | 1) General definitions 2) The VSEPR model 3) Qualitative molecular orbital diagrams 4) Closest packing, metal structures 5) The Structures of metalloids 6) Structures of the non-metals 7) Synthesis of the elements 8) Reactivity of the elements 9) Ionic Compounds 10) Ions in Solution 11) Element hydrogen compounds 12) Element halogen compounds 13) Element oxygen compounds 14) Redox chemistry | |||||
| Learning objective | Understanding of the fundamental principles of the structures, properties, and reactivities of the main group elements (groups 1,2 and 13 to 18). | |||||
| Content | The course is divided in 14 sections in which the fundamental phenomena of the chemistry of the main group elements are discussed: Part 1: Introduction in the periodical properties of the elements and general definitions –Part 2: The VSEPR model –Part 3: Qualitative molecular orbital diagrams for simple inorganic molecules – Part 4: Closest packing and structures of metals Part 5: The Structures of semimetals (metalloids) of the main group elements –Part 6: Structures of the non-metals– Part 7: Synthesis of the elements. –Part 8: Reactivity of the elements Part 9: Ionic Compounds Part 10: Ions in Solution Part 11: Element hydrogen compounds Part 12: Element halogen compounds Part 13: Element oxygen compounds Part 14: Redox chemistry. | |||||
| Lecture notes | The transparencies used in the course are accessible via the internet on Link | |||||
| Literature | J. Huheey, E. Keiter, R. Keiter, Inorganic Chemistry, Principles and Reactivity, 4th edition, deGruyter, 2003. C.E.Housecroft, E.C.Constable, Chemistry, 4th edition, Pearson Prentice Hall, 2010. | |||||
| Prerequisites / Notice | Basis for the understanding of this lecture is the course Allgemeine Chemie 1. | |||||
| 529-0012-03L | General Chemistry (Organic Chemistry) II | O | 4 credits | 3V + 1U | P. Chen | |
| Abstract | Classification of organic reactions, reactive intermediates: radicals, carbocations, carbanions, electrophilic aromatic substitution, electrophilic addition to double bonds, HSAB concept, nucleophilic substitution at sp3 hybridized carbon centres (SN1/SN2 reactions), nucleophilic aromatic substitutions, eliminations, oxidations, reductions. | |||||
| Learning objective | Understanding of fundamental reactivity principles and the relationship between structure and reactivity. Knowledge of the most important raection types and of selected classes of compounds. | |||||
| Content | Classification of organic reactions, reactive intermediates: radicals, carbocations, carbanions, electrophilic aromatic substitution, electrophilic addition to double bonds, HSAB concept, nucleophilic substitution at sp3 hybridized carbon centres (SN1/SN2 reactions), nucleophilic aromatic substitutions, eliminations, oxidations, reductions. | |||||
| Lecture notes | pdf file available at the beginning of the course | |||||
| Literature | [1] P. Sykes, "Reaktionsmechanismen der Organischen Chemie", VCH Verlagsgesellschaft, Weinheim 1988. [2] Carey/Sundberg, Advanced Organic Chemistry, Part A and B, 3rd ed., Plenum Press, New York, 1990/1991. Deutsch: Organische Chemie. [3] Vollhardt/Schore, Organic Chemistry, 2th ed., Freeman, New York, 1994 Deutsche Fassung: Organische Chemie 1995, Verlag Chemie, Wein¬heim, 1324 S. Dazu: N. Schore, Arbeitsbuch zu Vollhardt, Organische Chemie, 2. Aufl. Verlag Chemie, Weinheim, 1995, ca 400 S. [4] J. March, Advanced Organic Chemistry; Reactions, Mechanisms, and Structure, 5th ed., Wiley, New York, 1992. [5] Streitwieser/Heathcock, Organische Chemie, 2. Auflage, Verlag Chemie, Weinheim, 1994. [6] Streitwieser/Heathcock/Kosower, Introduction to Organic Chemistry, 4th ed., MacMillan Publishing Company, New York, 1992. [7] P. Y. Bruice, Organische Chemie, 5. Auflage, Pearson Verlag, 2007. | |||||
| 529-0012-01L | Physical Chemistry I: Thermodynamics | O | 4 credits | 3V + 1U | F. Merkt | |
| Abstract | Foundations of chemical thermodynamics. The first, second and third law of thermodynamics: Thermodynamic temperature scale, internal energy, enthalpy, entropy, the chemical potential. Solutions and mixtures, phase diagrams. Reaction thermodynamics: reaction parameters and equilibrium conditions, equilibrium constants. Thermodynamics of processes at surfaces and interfaces. | |||||
| Learning objective | Introduction to chemical thermodynamics | |||||
| Content | The first, second and third law of thermodynamics: empirical temperature and thermodynamic temperature scale, internal energy, entropy, thermal equilibrium. Models and standard states: ideal gases, ideal solutions and mixtures, real gases, real solutions and mixtures, activity, tables of standard thermodynamic quantities. Reaction thermodynamics: the chemical potential, reaction parameters and equilibrium conditions, equilibrium constants and their pressure and temperature dependence. Phase equilibria. Thermodynamics at surfaces and interfaces: Adsorption equilibria. Capillary forces. Adsorption isothermes. | |||||
| Lecture notes | See homepage of the lecture. | |||||
| Literature | See homepage of the lecture. | |||||
| Prerequisites / Notice | Requirements: Allgemeine Chemie I, Grundlagen der Mathematik | |||||
| 402-0044-00L | Physik II | O | 4 credits | 3V + 1U | J. Home | |
| Abstract | Introduction to the concepts and tools in physics with the help of demonstration experiments: electromagnetism, optics, introduction to modern physics. | |||||
| Learning objective | The concepts and tools in physics, as well as the methods of an experimental science are taught. The student should learn to identify, communicate and solve physical problems in his/her own field of science. | |||||
| Content | Electromagnetism (electric current, magnetic fields, electromagnetic induction, magnetic materials, Maxwell's equations) Optics (light, geometrical optics, interference and diffraction) Short introduction to quantum physics | |||||
| Lecture notes | The lecture follows the book "Physik" by Paul A. Tipler. | |||||
| Literature | Paul A. Tipler and Gene Mosca Physik Springer Spektrum Verlag | |||||
| 401-0272-00L | Mathematical Foundations I: Analysis B | O | 3 credits | 2V + 1U | L. Kobel-Keller | |
| Abstract | Basics about multidimensional analysis. Ordinary differential equations as mathematical models to describe processes (continuation from Analysis A). Numerical, analytical and geometrical aspects of differential equations. | |||||
| Learning objective | Introduction to calculus in several dimensions. Building simple models and analysing them mathematically. Knowledge of the basic concepts. | |||||
| Content | Basics about multidimensional analysis. Differential equations as mathematical models to describe processes. Numerical, analytical and geometrical aspects of differential equations. | |||||
| Literature | - G. B. Thomas, M. D. Weir, J. Hass: Analysis 2, Lehr- und Übungsbuch, Pearson-Verlag - D. W. Jordan, P. Smith: Mathematische Methoden für die Praxis, Spektrum Akademischer Verlag - M. Akveld/R. Sperb: Analysis I, Analysis II (vdf) - L. Papula: Mathematik für Ingenieure und Naturwissenschaftler Bde 1,2,3. (Vieweg) Further reading suggestions will be indicated during the lecture. | |||||
| 401-0622-00L | Mathematical Foundations II: Linear Algebra and Statistics | O | 3 credits | 2V + 1U | M. Dettling | |
| Abstract | Systems of linear equations; matrix algebra, determinants; vector spaces, norms and scalar products; linear maps, basis transformations; eigenvalues and eigenvectors. Random variables and probability, discrete and continuous distribution models; expectation, variance, central limit theorem, parameter estimation; statistical hypothesis tests; confidence intervals; regression analysis. | |||||
| Learning objective | A sound knowledge of mathematics is an essential prerequisite for a quantitative and computer-based approach to natural sciences. In an intensive two-semester course the most important basic concepts of mathematics, namely univariate and multivariate calculus, linear algebra and statistics are taught. | |||||
| Content | Systems of linear equations; matrix algebra, determinants; vector spaces, norms and scalar products; linear maps, basis transformations; eigenvalues and eigenvectors. - Least squares fitting and regression models; random variables, statistical properties of least-squares estimators; tests, confidence and prediction intervals in regression models; residual analysis. | |||||
| Lecture notes | For the part on Linear Algebra, there is a short script (in German) which summarizes the main concepts and results without examples. For a self-contained presentation, the book by Nipp and Stoffer should be used. For the part on Statistics there is a detailed script (in German) available which should be self-contained. The book by Stahel can be used for additional information. | |||||
| Literature | Linear Algebra: K. Nipp/D. Stoffer: "Lineare Algebra", vdf, 5th edition, 2002. Statistics: W. Stahel, "Statistische Datenanalyse", Vieweg, 5rd edition, 2008. | |||||
| Laboratory Courses | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0230-00L | Inorganic and Organic Chemistry I  Enrolment only possible up to the beginning of the semester. | O | 8 credits | 12P | J. W. Bode, M. Jackl, V. R. Pattabiraman | |
| Abstract | Laboratory Course in Inorganic and Organic Chemistry I | |||||
| Learning objective | Introduction into basic techniques used in the organic laboratory. Understanding organic reactions through experiments. | |||||
| Content | Part I: Basic operations such as the isolation, purification and characterization of organic compounds: distillation, extraction, chromatography, crystallization, IR (UV/1H-NMR)-spectroscopy for the identification of the constituion of organic compounds. Part II: Organic reactions: preparative chemistry. From simple, one-step to multistep syntheses. Both classic and modern reactions will be performed. Part III: Preparation of a chiral, enantiomerically pure ligand for asymmetric catalysis (together with AOCP II) | |||||
| Literature | - R. K. Müller, R. Keese: "Grundoperationen der präparativen organischen Chemie"; J. Leonard, B. Lygo, G. Procter: "Praxis der Organischen Chemie" (Übersetzung herausgegeben von G. Dyker), VCH, Weinheim, 1996, ISBN 3-527-29411-2. | |||||
| Prerequisites / Notice | Prerequisites: - Praktikum Allgemeine Chemie (1. Semester, 529-0011-04/05) - Vorlesung Organische Chemie I (1. Semester, 529-0011-03) | |||||
| Bachelor Studies (Programme Regulations 2005) | ||||||
| 4. Semester | ||||||
| Compulsory Subjects Examination Block I | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0122-00L | Inorganic Chemistry II | O | 3 credits | 3G | M. Kovalenko | |
| Abstract | The lecture is based on Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers, i.e. crystal structures. | |||||
| Learning objective | The lecture follows Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers. | |||||
| Content | Symmetry aspects of chemical bonding, point groups and representations for the deduction of molecular orbitals, energy assessment for molecules and solids, Sanderson formalism, derivation and understanding of band structures, densities of states, overlap populations, crystal symmetry, basic crystal structures and corresponding properties, visual representations of crystal structures. | |||||
| Lecture notes | see Moodle | |||||
| Literature | 1. I. Hargittai, M. Hargittai, "Symmetry through the Eyes of a Chemist", Plenum Press, 1995; 2. R. Hoffmann, "Solids and Surfaces", VCH 1988; 3. U. Müller, "Anorganische Strukturchemie", 6. Auflage, Vieweg + Teubner 2008 | |||||
| Prerequisites / Notice | Requirements: Inorganic Chemistry I | |||||
| 529-0222-00L | Organic Chemistry II | O | 3 credits | 2V + 1U | J. W. Bode, B. Morandi | |
| Abstract | This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. These topics are combined to the planning and execution of multiple step syntheses of complex molecules. | |||||
| Learning objective | Goals of this course include the a deeper understanding of basic organic reactions and mechanism as well as advanced and catalytic transformations (for example, Mitsunobu reactions, Corey-Chaykovsky epoxidation, Stetter reactions, etc). Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, and introduced, with an emphasis on their catalytic cycles and elementrary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines. | |||||
| Content | Oxidation and reduction of organic compounds, redox netural reactions and rearrangments, advanced transformations of functional groups and reaction mechanismes, kinetic and thermodynamic control of organic reactions, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, introduction to peptide synthesis and protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reaction. | |||||
| Lecture notes | The lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link: http://www.bode.ethz.ch/education.html | |||||
| Literature | Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012. | |||||
| 529-0431-00L | Physical Chemistry III: Molecular Quantum Mechanics | O | 4 credits | 4G | B. H. Meier, M. Ernst | |
| Abstract | Postulates of quantum mechanics, operator algebra, Schrödinger's equation, state functions and expectation values, matrix representation of operators, particle in a box, tunneling, harmonic oscillator, molecular vibrations, angular momentum and spin, generalised Pauli principle, perturbation theory, electronic structure of atoms and molecules, Born-Oppenheimer approximation. | |||||
| Learning objective | This is an introductory course in quantum mechanics. The course starts with an overview of the fundamental concepts of quantum mechanics and introduces the mathematical formalism. The postulates and theorems of quantum mechanics are discussed in the context of experimental and numerical determination of physical quantities. The course develops the tools necessary for the understanding and calculation of elementary quantum phenomena in atoms and molecules. | |||||
| Content | Postulates and theorems of quantum mechanics: operator algebra, Schrödinger's equation, state functions and expectation values. Linear motions: free particles, particle in a box, quantum mechanical tunneling, the harmonic oscillator and molecular vibrations. Angular momentum: electronic spin and orbital motion, molecular rotations. Electronic structure of atoms and molecules: the Pauli principle, angular momentum coupling, the Born-Oppenheimer approximation. Variational principle and perturbation theory. Discussion of bigger systems (solids, nano-structures). | |||||
| Lecture notes | A script written in German will be distributed. The script is, however, no replacement for personal notes during the lecture and does not cover all aspects discussed. | |||||
| 529-0058-00L | Analytical Chemistry II | O | 3 credits | 3G | D. Günther, T. Bucheli, M.‑O. Ebert, P. Lienemann, G. Schwarz | |
| Abstract | Enhanced knowledge about the elemental analysis and spectrocopical techniques with close relation to practical applications. This course is based on the knowledge from analytical chemistry I. Separation methods are included. | |||||
| Learning objective | Use and applications of the elemental analysis and spectroscopical knowledge to solve relevant analytical problems. | |||||
| Content | Combined application of spectroscopic methods for structure determination, and practical application of element analysis. More complex NMR methods: recording techniques, application of exchange phenomena, double resonance, spin-lattice relaxation, nuclear Overhauser effect, applications of experimental 2d and multipulse NMR spectroscopy, shift reagents. Application of chromatographic and electrophoretic separation methods: basics, working technique, quality assessment of a separation method, van-Deemter equation, gas chromatography, liquid chromatography (HPLC, ion chromatography, gel permeation, packing materials, gradient elution, retention index), electrophoresis, electroosmotic flow, zone electrophoresis, capillary electrophoresis, isoelectrical focussing, electrochromatography, 2d gel electrophoresis, SDS-PAGE, field flow fractionation, enhanced knowledge in atomic absorption spectroscopy, atomic emission spectroscopy, X-ray fluorescence spectroscopy, ICP-OES, ICP-MS. | |||||
| Lecture notes | Script will be available | |||||
| Literature | Literature will be within the script. | |||||
| Prerequisites / Notice | Exercises for spectra interpretation are part of the lecture. In addition the lecture 529-0289-00 "Instrumentalanalyse organischer Verbindungen" (4th semester) is recommended. Prerequisite: 529-0051-00 "Analytische Chemie I" (3rd semester) | |||||
| 529-0625-00L | Chemical Engineering | O | 3 credits | 3G | W. J. Stark | |
| Abstract | Chemical Engineering provides an introduction to production and process design. Beyond different types and operation of chemical or bio-reactors, issues of scaling, new synthesis methods and problems of industrial production are addressed. An introduction in heterogeneous catalysis and transport of impulse, mass and energy connect the new concepts to the basic education in chemistry and biology. | |||||
| Learning objective | Intended for chemists, chemical engineers, biochemists and biologists, the course Chemical and Bioengineering 4th semester addresses the basics of production and process design. Starting with different reactors, process steps and unit operations in production, the industrial scale usage of chemicals and reagents are discussed and further illustrated by examples. Material and energy balances and the concept of selectivity are used to broaden the students view on the complexity of production and show how modern engineering can contribute to an environmentally sustainable production. In the second part of the lecture, reactors, single cells or living matter are discussed in terms of transport properties. Beyond metabolism or chemical processes, transport of impulse, mass and energy heavily influence chemical and biological processes. They are introduced simultaneously and provide a basis for the understanding of flow, diffusion and heat transport. Dimensionless numbers are used to implement transport properties in unit operations and process design. An introduction to heterogeneous catalysis connects the acquired concepts to chemistry and biology and shows how powerful new processes arise from combining molecular understanding and transport. | |||||
| Content | Elements of chemical transformations: preparation of reactants, reaction process, product work-up and recycling, product purification; continuous, semibatch and batch processes; material balances: chemical reactors and separation processes, multiple systems and multistage systems; energy balances: chemical reactors and separation processes, enthalpy changes, coupled material and energy balances; multiple reactions: optimisation of reactor performance, yield and selectivity; mass transport and chemical reaction: mixing effects in homogeneous and heterogeneous systems, diffusion and reaction in porous materials; heat exchange and chemical reaction: adiabatic reactors, optimum operating conditions for exothermic and endothermic equilibrium reactions, thermal runaway, reactor size and scale up. | |||||
| Lecture notes | Supporting material to the course is available on the homepage www.fml.ethz.ch | |||||
| Literature | Literature and text books are announced at the beginning of the course. | |||||
| 402-0084-00L | Physics II | O | 4 credits | 3V + 1U | G. Dissertori | |
| Abstract | This course is an introduction to classical physics, with special focus on applications in medicine. | |||||
| Learning objective | Obtain an understanding of basic concepts in classical physics and their application (using mathematical pre-knowledge) to the solution of simple problems, including certain applications in medicine. Obtain an understanding of relevant quantities and of orders of magnitude. | |||||
| Content | Electromagnetism; Thermodynamics; Optics. | |||||
| Lecture notes | Will be distributed at the start of the semester. | |||||
| Literature | "Physik für Mediziner, Biologen, Pharmazeuten", von Alfred Trautwein, Uwe Kreibig, Jürgen Hüttermann; De Gruyter Verlag. | |||||
| Prerequisites / Notice | Voraussetzung Mathematik I+II (Studiengänge Gesundheitswissenschaften und Technologie bzw. Humanmedizin) / Mathematik-Lehrveranstaltungen des Basisjahres (Studiengänge Chemie, Chemieingenieurwissenschaften bzw. Interdisziplinäre Naturwissenschaften) | |||||
| Laboratory Courses | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0054-00L | Physical and Analytical Chemistry | O | 10 credits | 15P | E. C. Meister, R. Zenobi, M. Badertscher, M.‑O. Ebert, B. Hattendorf, Y. Yamakoshi | |
| Abstract | Practical introduction to important experimental methods in physical and analytical chemistry. | |||||
| Learning objective | The students have to carry out selected experiments in physical chemistry and evaluate measurement data. They acquire a good knowledge about the most important practical techniques in analytical chemistry. Laboratory reports have to be written to each experiment. | |||||
| Content | Physical chemistry part: Short recapitulation of statistics and analysis of measurement data. Writing experimental reports with regard to publication of scientific works. Basic physical chemistry experiments (a maximum of six experiments form the following themes): 1. Phase diagrams (liquid-vapour and solid-liquid phase diagrams, cryoscopy); 2. electrochemistry and electronics; 3. quantum chemistry studies; 4. kinetics; 5. thermochemistry; 6. speed of sound in gases and liquids; 7. surface tension. Analytical chemistry part: 1. Introduction to the concept of sampling, quantitative elemental analysis and trace analysis, atomic spectroscopic methods, comparative measurements with electrochemical methods; 2. Separation methods, their principles and optimisation: comparison of the different chromatographic methods, effect of the stationary and mobile phases, common errors/artefacts, liquid chromatography, gas chromatography (injection methods). 3. Spectroscopic methods in organic structure determination: recording of IR and UV/VIS spectra, recording technique in NMR Mandatory exercises in spectroscopy in an accompanying tutorial 529-0289-00 "Instrumentalanalyse organischer Verbindungen" are an integral part of this course. | |||||
| Lecture notes | Descriptions for experiments available online. | |||||
| Literature | Für PC-Teil: Erich Meister, Grundpraktikum Physikalische Cheme, 2. Aufl. Vdf UTB, Zürich 2012. | |||||
| Prerequisites / Notice | Prerequisites: 529-0051-00 "Analytische Chemie I (3. Semester)" 529-0058-00 "Analytische Chemie II (4. Semester)" in parallel to the lab class, or completed in an earlier semester. The course 529-0289-00L "Instumentalanalyse organischer Verbindungen" is an obligatory component of the lab class / praktikum. | |||||
| 6. Semester | ||||||
| Compulsory Subjects Examination Block II | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0131-00L | Inorganic Chemistry IV: (Nano-)Materials; Synthesis, Properties and Surface Chemistry | O | 4 credits | 3G | C. Copéret, A. Comas Vives | |
| Abstract | Introduction into Solid State Chemistry, to the synthesis and properties of solids and to Nanomaterials. | |||||
| Learning objective | Introduction into solid compounds and nanomaterials: syntheses, properties and applications. | |||||
| Content | Section 1. Generalities – Prof. C. Copéret How do we apprehend a solid? Bulk vs. Surface Texture, Surface area (N2 adsorption, BET), Crystallinity (X-ray diffraction), Surface functionalities (IR, NMR), Acidity/Basicity (Probe molecules: pyridine, CO, CO2…), Point of Zero Electric Charge Section 2. Materials – Prof. C. Copéret 2.1 Synthetic methods 2.2 Sol-Gel and Solution Chemistry of Solids Section 3. Metal oxides – Prof. C. Copéret 3.1 Silica (SiO2) 3.2 Alumina (Al2O3) 3.3 Aluminosilicates (amorphous, layered materials and zeolites) 3.4. Mesostructured and hybrid materials 3.5 Semi-conducting and conducting oxides (e.g TiO2 and related materials, IrO2) 3.6 Other materials: Single and Complex Oxides, (MgO, CaO, MgAlO2, Perovskites), Polyoxometallates Section 4. Other materials Metal halides and chalcogenides Carbon-based materials Metals and Alloys Section 5. Bonding in Solids and Surfaces – Dr. Comas-Vives | |||||
| Lecture notes | is provided on the internet. | |||||
| Literature | A. West, Solid State Chemistry and its Applications, Wiley 1989; U. Müller, Anorganische Strukturchemie, Teubner Taschenbuch 2006; R. Nesper, H.-J. Muhr, Chimia 52 (1998) 571; C.N.R. Rao, A. Müller, A.K. Cheetham, Nanomaterials, Wiley-VCH 2007. | |||||
| Prerequisites / Notice | AC-II | |||||
| 529-0232-00L | Organic Chemistry IV: Physical Organic Chemistry | O | 4 credits | 2V + 1U | P. Chen, R. Poranne | |
| Abstract | Introduction to qualitative molecular orbital theory as applied to organic reactivity. Hückel theory, perturbation theory, molecular symmetry. Frontier orbital theory and stereoelectronic effects. Pericyclic reactions, photochemistry | |||||
| Learning objective | Introduction to theoretical methods in organic chemistry | |||||
| Content | Qualitative MO theory and its application to organic reactions, thermal rearrangements, pericyclic reactions. | |||||
| 529-0434-00L | Physical Chemistry V: Spectroscopy | O | 4 credits | 3G | R. Signorell | |
| Abstract | Absorption and scattering of electromagnetic radiation; transition probabilities, rate equations; Einstein coefficients and lasers; selection rules and symmetry; band shape, energy transfer, and broadening mechanisms; atomic spectroscopy; molecular spectroscopy: vibration and rotation; spectroscopy of clusters, nanoparticles and condensed phases | |||||
| Learning objective | The lecture is devoted to atomic, molecular, and condensed phase spectroscopy treating both theoretical and experimental aspects. The focus is on the interaction between electromagnetic radiation and matter. | |||||
| Content | Absorption and scattering of electromagnetic radiation; transition probabilities, rate equations; Einstein coefficients and lasers; selection rules and symmetry; band shape, energy transfer, and broadening mechanisms; atomic spectroscopy; molecular spectroscopy: vibration and rotation; spectroscopy of clusters, nanoparticles and condensed phases | |||||
| Lecture notes | is partly available | |||||
| 529-0580-00L | Safety, Environmental Aspects and Risk Management This course has been offered with a new title (before: Risk Analysis of Chemical Processes and Products) and by new lecturers (before Prof. Hungerbühler) since spring semester 2018. | O | 4 credits | 3G | S. Kiesewetter, K. Timmel | |
| Abstract | Overview of the impact of industrial activities on the environment and human beings; required risk assessments and preventive measures as well as an insight on the fundamentals of Swiss legislation (environment / occupational safety). | |||||
| Learning objective | Basic understanding of the impact of industrial activities on human beings and the environment; raise awareness for risks and safety concerns. | |||||
| Content | Geschichtliche Aspekte der Ökotoxikologie / Erkenntnisse aus der Vergangenheit; Zusammenhänge Toxikologie-Ökotoxikologie; Risikoanalysen – wozu braucht es eine Risikoanalyse? Kennenlernen der Hilfsmittel zur Erarbeitung einer Risikoanalyse, Besprechung konkreter Beispiele; Einblick in die relevanten gesetzlichen Grundlagen (Schwerpunkt Schweizer Gesetzgebung) der Bereiche Umwelt und Arbeitssicherheit / Wie finde ich was ich suche? Wie finde ich mich in den Gesetztestexten zurecht? Hinweise zu weiteren nützlichen Hilfsmitteln zur Beurteilung der Auswirkungen auf Mensch und Umwelt; Aufbau einer Sicherheitsorganisation in einem Unternehmen, an einer Hochschule. | |||||
| Lecture notes | Wird bei der ersten Vorlesung zur Verfügung gestellt. | |||||
| Literature | Ergänzungsliteratur wird im Skript angegeben. | |||||
| Prerequisites / Notice | Im Rahmen der Vorlesung wird eine Gruppenarbeit im Sinne eines Leistungselementes durchgeführt, die benotet wird. Die Schlussnote setzt sich wie folgt zusammen: Gruppenarbeit (Gewichtung 50%) und schriftlicher Prüfung (50%) Bei Wiederholung der schriftlichen Prüfung kann das Resultat der Gruppenarbeit aus einem früheren Semester übernommen werden. | |||||
| Laboratory Courses and Research Projects Students enrolled in the 6th semester of the Bachelor's programme in Chemistry at ETH are admitted to complete laboratory practicals and up to two research projects in the Master's elective/core subject areas. This applies solely to students with a maximum of 60 missing credits for the Bachelor's diploma. | ||||||
| Electives | ||||||
| Inorganic Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0142-00L | Advanced Organometallic and Coordination Chemistry: Learning from Nature and Industrial Processes Prerequisites: successful participation in 529-0132-00L "Inorganic Chemistry III: Organometallic Chemistry and Homogeneous Catalysis". | W | 6 credits | 3G | V. Mougel, C. Copéret | |
| Abstract | This class will discuss advanced concepts in organometallic, bio-inorganic and coordination chemistry, in the context of homogeneous and heterogeneous catalysis as well as enzymatic processes. The class will thus cover a broad range of catalytic transformations focusing on the sustainable and efficient use of feedstock molecules, exploring the parallel between industrial and biological systems. | |||||
| Learning objective | Gain knowledge of catalytic transformations, relevant to processes found in industry and in Nature. Development of an extended molecular understanding of organometallic, bio-inorganic and coordination chemistry in relation to catalytic transformations. | |||||
| Content | Specific focus will be given to key reactions such as alkane functionalization and homologation, olefin metathesis and polymerization, oxidation, processes related to conversion of C1 molecules (CH4 and CO2), CO/H2 to hydrocarbons (Fischer-Tropsch) and N2/H2 to ammonia (Haber-Bosch) as well as the corresponding enzymatic counterparts. The fundamental underlying principle of the associated elementary steps and reaction mechanisms involved in these processes, that include C-H activation, O/N-atom transfer reactions, N-N, C-O and C-C bond cleavage and formation will be discussed in details exploiting Molecular Orbital theory and spectroscopy. | |||||
| Lecture notes | A script is provided on Ilias. It is expected that the students will consult the accompanying literature. | |||||
| Literature | Books 1) R. Crabtree: the Organometallic Chemistry of Transition Metals – Wiley, 5th Edition 2) TA Albright, JB Burdett, MH Whangbo: Orbital Interactions in Chemistry – Wiley Interscience 3) Moore and Janes: Metal-Ligand Bonding – Oxford Chemistry Primers 4) Lippart and Berg: Principles of Bio-inorganic Chemistry – Wiley | |||||
| Prerequisites / Notice | it is expected that students will have knowledge of AC-III or similar class/level. | |||||
| Organic Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0242-00L | Supramolecular Chemistry | W | 6 credits | 3G | Y. Yamakoshi, B. M. Lewandowski | |
| Abstract | Principles of molecular recognition: cation/anion complexation and their technological applications; complexation of neutral molecules in aqueous solution; non-covalent interactions involving aromatic rings; hydrogen bonding; molecular sef-assembly - a chemical approach towards nanostructures; thermodynamics and kinetics of complexation processes; synthesis of receptors; template effects. | |||||
| Learning objective | The objective of this class is to reach an understanding of the nature and magnitude of the intermolecular interactions and solvation effects that provide the driving force for the association between molecules and/or ions induced by non-covalent bonding interactions. The lecture (2 h) is complemented by a problem solving class (1 h) which focuses on receptor syntheses and other synthetic aspects of supramolecular chemistry. | |||||
| Content | Principles of molecular recognition: cation complexation, anion complexation, cation and anion complexation in technological applications, complexation of neutral molecules in aqueous solution, non-covalent interactions involving aromatic rings, hydrogen bonding, molecular sef-assembly - a chemical approach towards nanostructures, thermodynamics and kinetics of complexation processes, synthesis of receptors, template effects. | |||||
| Lecture notes | Printed lecture notes will be available for purchase at the beginning of the class. Problem sets and answer keys will be available on-line. | |||||
| Literature | No compulsory textbooks. Literature for further reading will be presented during the class and cited in the lecture notes. | |||||
| Prerequisites / Notice | Course prerequisite: classes in organic and physical chemistry of the first two years of studies. | |||||
| Physical Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0442-00L | Advanced Kinetics | W | 6 credits | 3G | H. J. Wörner, J. Richardson | |
| Abstract | This lecture covers the theoretical foundations of quantum dynamics and its application to chemical reaction kinetics. In the second part the experimental methods of time-resolved molecular spectroscopy are introduced. | |||||
| Learning objective | This lecture provides the conceptual foundations of chemical reaction dynamics and shows how primary molecular processes can be studied by theoretical simulation and experiment. | |||||
| Content | In the first part, the theory of quantum dynamics is derived from the time-dependent Schrödinger equation. The theory is illustrated with molecular examples including tunnelling, recurrences, nonadiabatic crossings. A rigorous rate theory is obtained both from a quantum-mechanical picture as well as within the classical approximation. The approximations leading to conventional transition-state theory for polyatomic reactions are discussed. In this way, relaxation and irreversibility will be explained which are at the foundation of statistical mechanics. In the second part, three-dimensional scattering theory is introduced and applied to discuss molecular collisions and photoionization. Experimental techniques for the study of photochemical primary processes, photochemical reactions and chemical reaction dynamics are introduced (time-resolved spectroscopies on nano- to attosecond time scales, molecular beam methods). Finally, the quantum dynamics of systems with a very large number of quantum states are discussed, introducing the Pauli equations and the Pauli entropy. | |||||
| Lecture notes | Will be available online. | |||||
| Literature | D. J. Tannor, Introduction to Quantum Mechanics: A Time-Dependent Perspective R. D. Levine, Molecular Reaction Dynamics S. Mukamel, Principles of Nonlinear Optical Spectroscopy Z. Chang, Fundamentals of Attosecond Optics | |||||
| Prerequisites / Notice | 529-0422-00L Physical Chemistry II: Chemical Reaction Dynamics | |||||
| 529-0440-00L | Physical Electrochemistry and Electrocatalysis | W | 6 credits | 3G | T. Schmidt | |
| Abstract | Fundamentals of electrochemistry, electrochemical electron transfer, electrochemical processes, electrochemical kinetics, electrocatalysis, surface electrochemistry, electrochemical energy conversion processes and introduction into the technologies (e.g., fuel cell, electrolysis), electrochemical methods (e.g., voltammetry, impedance spectroscopy), mass transport. | |||||
| Learning objective | Providing an overview and in-depth understanding of Fundamentals of electrochemistry, electrochemical electron transfer, electrochemical processes, electrochemical kinetics, electrocatalysis, surface electrochemistry, electrochemical energy conversion processes (fuel cell, electrolysis), electrochemical methods and mass transport during electrochemical reactions. The students will learn about the importance of electrochemical kinetics and its relation to industrial electrochemical processes and in the energy seactor. | |||||
| Content | Review of electrochemical thermodynamics, description electrochemical kinetics, Butler-Volmer equation, Tafel kinetics, simple electrochemical reactions, electron transfer, Marcus Theory, fundamentals of electrocatalysis, elementary reaction processes, rate-determining steps in electrochemical reactions, practical examples and applications specifically for electrochemical energy conversion processes, introduction to electrochemical methods, mass transport in electrochemical systems. Introduction to fuel cells and electrolysis | |||||
| Lecture notes | Will be handed out during the Semester | |||||
| Literature | Physical Electrochemistry, E. Gileadi, Wiley VCH Electrochemical Methods, A. Bard/L. Faulkner, Wiley-VCH Modern Electrochemistry 2A - Fundamentals of Electrodics, J. Bockris, A. Reddy, M. Gamboa-Aldeco, Kluwer Academic/Plenum Publishers | |||||
| Analytical Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0042-00L | Structure Elucidation by NMR | W | 4 credits | 2G | M.‑O. Ebert | |
| Abstract | Structure Elucidation of Complex Organic Molecules by NMR | |||||
| Learning objective | Structure elucidation of complex organic molecules (including peptides, oligosaccharides and oligonucleotides) by advanced 1D and 2D NMR spectroscopy. The emphasis of the course is on the selection of optimal strategies for the solution of a given problem, spectrum interpretation and possible artifacts. Solving and discussing practical case studies/problems demonstrating the individual methods and, in the last third of the course, the combined application of several methods form an important part of the course. | |||||
| Content | Structure determination by multi-pulse and 2D NMR spectroscopy. Homonuclear and heteronuclear shift correlation through scalar coupling; one and two dimensional methods based on the nuclear Overhauser effect. Choosing the best strategy for a given problem, interpretation and artefacts. | |||||
| Lecture notes | Scripts (in English) are distributed in the course | |||||
| Literature | T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistry, Pergamon Press, 1999 (NMR part) Further reading and citations are listed in the script. | |||||
| Prerequisites / Notice | The course language is English. Required level: Courses in analytical chemistry of the 2nd year or equivalent. | |||||
| Biological Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0732-00L | Proteins and Lipids | W | 6 credits | 3G | D. Hilvert | |
| Abstract | An overview of the relationship between protein sequence, conformation and function. | |||||
| Learning objective | Overview of the relationship between protein sequence, conformation and function. | |||||
| Content | Proteins, structures and properties, (bio)synthesis of polypeptides, protein folding and design, protein engineering, chemical modification of proteins, proteomics. | |||||
| Literature | General Literature: - T.E. Creighton: Proteins: Structures and Molecular Properties, 2nd Edition, H.W. Freeman and Company, New York, 1993. - C. Branden, J. Tooze , Introduction to Protein Structure, Garland Publishing, New York, 1991. - J. M. Berg, J. L. Tymoczko, L. Stryer: Biochemistry, 5th edition, H.W. Freeman and Company, New York, 2002. - G.A. Petsko, D. Ringe: Protein Structure and Function, New Science Press Ltd., London, 2004. Original Literature: Citations from the original literature relevant to the individual lectures will be assigned weekly. | |||||
| Chemical Aspects of Energy | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0191-01L | Renewable Energy Technologies II, Energy Storage and Conversion The lectures Renewable Energy Technologies I (529-0193-00L) and Renewable Energy Technologies II (529-0191-01L) can be taken independently from one another. | W | 4 credits | 3G | T. Schmidt, L. Gubler | |
| Abstract | Global & Swiss energy system. Storage: Pumped water, flywheels, compressed air. Hydrogen as energy carrier; electrolysis; power-to-gas. Fuel cells: from fundamentals to systems; Fuel cell vehicles; electrochemical storage in batteries. supercapacitors and redox flow cells; electromobility. The main focus of the lecture will be on electrochemical energy conversion and storage. | |||||
| Learning objective | Students will recognize the importance of energy storage in an industrial energy system, specifically in the context of a future system based on renewable sources. The efficient generation of electricity from hydrogen in fuel cells, and the efficient energy storage in batteries and supercapacitors will be introduced. Students will get a detailed insight into electrochemical energy conversion and storage, which will play an important role in future energy systems. | |||||
| Literature | - Tester, J.W., Drake, E.M., Golay, M.W., Driscoll, M.J., Peters, W.A.: Sustainable Energy - Choosing Among Options (MIT Press, 2005). - C.H. Hamann, A. Hamnett, W. Vielstich; Electrochemistry, Wiley-VCH (2007). - K. Krischer, K. Schönleber: Physiccs of Energy Conversion, De Gruyter (2015) - R. Schlögl, Chemical Energy Storage, De Gruyter (2013) | |||||
| Prerequisites / Notice | Please note that this is a 3 hours/week lecture including exercises, i.e., exercises will be included and are not separated. It is therefore highly recommended to attend the full 3 hours every week. Participating students are required to have basic knowlegde of chemistry and thermodynamics. | |||||
| Computational Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0474-00L | Quantum Chemistry | W | 6 credits | 3G | M. Reiher, T. Weymuth | |
| Abstract | Introduction into the basic concepts of electronic structure theory and into numerical methods of quantum chemistry. Exercise classes are designed to deepen the theory; practical case studies using quantum chemical software to provide a 'hands-on' expertise in applying these methods. | |||||
| Learning objective | Nowadays, chemical research can be carried out in silico, an intellectual achievement for which Pople and Kohn have been awarded the Nobel prize of the year 1998. This lecture shows how that has been accomplished. It works out the many-particle theory of many-electron systems (atoms and molecules) and discusses its implementation into computer programs. A complete picture of quantum chemistry shall be provided that will allow students to carry out such calculations on molecules (for accompanying experimental work in the wet lab or as a basis for further study of the theory). | |||||
| Content | Basic concepts of many-particle quantum mechanics. Derivation of the many-electron theory for atoms and molecules; starting with the harmonic approximation for the nuclear problem and with Hartree-Fock theory for the electronic problem to Moeller-Plesset perturbation theory and configuration interaction and to coupled cluster and multi-configurational approaches. Density functional theory. Case studies using quantum mechanical software. | |||||
| Lecture notes | Hand outs in German will be provided for each lecture (they are supplemented by (computer) examples that continuously illustrate how the theory works). Please navigate to the lecture material starting here: https://reiher.ethz.ch/courses-and-seminars/exercises.html | |||||
| Literature | Textbooks on Quantum Chemistry: F.L. Pilar, Elementary Quantum Chemistry, Dover Publications I.N. Levine, Quantum Chemistry, Prentice Hall Hartree-Fock in basis set representation: A. Szabo and N. Ostlund, Modern Quantum Chemistry: Introduction to Advanced Electronic Structure Theory, McGraw-Hill Textbooks on Computational Chemistry: F. Jensen, Introduction to Computational Chemistry, John Wiley & Sons C.J. Cramer, Essentials of Computational Chemistry, John Wiley & Sons | |||||
| Prerequisites / Notice | Basic knowledge in quantum mechanics (e.g. through course physical chemistry III - quantum mechanics) required | |||||
| Materials Science | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 327-1206-00L | Advanced Building Blocks for Soft Materials | W | 5 credits | 4G | J. Vermant, A. D. Schlüter | |
| Abstract | Part 1 of the course (Spring semester) focuses on the chemistry of the building blocks and to learn how structures can be manipulated by chemistry, composition and phase behaviour. The goal is to learn what can be done, both in an idealized research environment and in the realm of industrial scale production. | |||||
| Learning objective | The goal of the two courses combined is to present the students with a toolbox for materials engineers to design, study and make soft materials. | |||||
| Content | Where physics, chemistry and biology meet engineering. | |||||
| Lecture notes | Copies of the slides and a set of lecture notes will be provided. | |||||
| Literature | For the first and the second part combined there are a few books of recommended reading, but their is no textbook that we will rigorously follow. Introduction to Soft Matter: Synthetic and Biological Self-Assembling Materials Paperback by Ian W. Hamley ISBN-13: 978-0470516102 ISBN-10: 0470516100 Structured Fluids: Polymers, Colloids, Surfactants by Thomas A. Witten, Philip A. Pincus (OXford) ISBN-13: 978-0199583829 ISBN-10: 019958382X | |||||
| Industrial Chemistry | ||||||
| Number | Title | Type | ECTS | Hours | Lecturers | |
| 529-0192-00L | Industrial Chemistry Replacement for 529-0502-00L Catalysis | W | 4 credits | 3G | J. A. van Bokhoven, M. Ranocchiari | |
| Abstract | The lecture will describe how the most important chemicals and intermediates are produced from both a chemical and chemical engineering point of view. Reaction mechanisms up to reactor design will be covered. | |||||
| Learning objective | Basic knowledge of reaction mechanisms and reactor design of the most important chemicals and intermediates. | |||||
| Content | The vast majority of all intermediates and chemicals originate from coal, oil or gas. The development of these processes over a time span of more than hundred years has resulted in fascinating chemistry and processes. The lecture will describe how the most important chemicals and intermediates are produced from both a chemical and chemical engineering point of view. Reaction mechanisms up to reactor design will be covered. | |||||
| Lecture notes | Supplemental material will be available on the webpage: http://www.vanbokhoven.ethz.ch/education.html | |||||
| Literature | Hans-Jürgen Arpe, Industrial Organic Chemistry, 5th Edition, Wyley-VCH, 2010 G. P. Chiusoli, P. M. Maitlis, Metal-catalysis in Industrial Organic Processes, RSC Publishing, 2008 | |||||
| GESS Science in Perspective | ||||||
| Science in Perspective | ||||||
| » see Science in Perspective: Type A: Enhancement of Reflection Capability | ||||||
| » Recommended Science in Perspective (Type B) for D-CHAB | ||||||
| Language Courses | ||||||
| » see Science in Perspective: Language Courses ETH/UZH | ||||||