Search result: Catalogue data in Spring Semester 2019
Chemistry Bachelor ![]() | ||||||
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Number | Title | Type | ECTS | Hours | Lecturers | |
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529-0122-00L | Inorganic Chemistry II | O | 3 credits | 3G | M. Kovalenko | |
Abstract | The lecture is based on Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers, i.e. crystal structures. | |||||
Learning objective | The lecture follows Inorganic Chemistry I and addresses an enhanced understanding of the symmetry aspects of chemical bonding of molecules and translation polymers. | |||||
Content | Symmetry aspects of chemical bonding, point groups and representations for the deduction of molecular orbitals, energy assessment for molecules and solids, Sanderson formalism, derivation and understanding of band structures, densities of states, overlap populations, crystal symmetry, basic crystal structures and corresponding properties, visual representations of crystal structures. | |||||
Lecture notes | see Moodle | |||||
Literature | 1. I. Hargittai, M. Hargittai, "Symmetry through the Eyes of a Chemist", Plenum Press, 1995; 2. R. Hoffmann, "Solids and Surfaces", VCH 1988; 3. U. Müller, "Anorganische Strukturchemie", 6. Auflage, Vieweg + Teubner 2008 | |||||
Prerequisites / Notice | Requirements: Inorganic Chemistry I | |||||
529-0222-00L | Organic Chemistry II | O | 3 credits | 2V + 1U | J. W. Bode, B. Morandi | |
Abstract | This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. These topics are combined to the planning and execution of multiple step syntheses of complex molecules. | |||||
Learning objective | Goals of this course include the a deeper understanding of basic organic reactions and mechanism as well as advanced and catalytic transformations (for example, Mitsunobu reactions, Corey-Chaykovsky epoxidation, Stetter reactions, etc). Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, and introduced, with an emphasis on their catalytic cycles and elementrary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines. | |||||
Content | Oxidation and reduction of organic compounds, redox netural reactions and rearrangments, advanced transformations of functional groups and reaction mechanismes, kinetic and thermodynamic control of organic reactions, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, introduction to peptide synthesis and protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reaction. | |||||
Lecture notes | The lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link: http://www.bode.ethz.ch/education.html | |||||
Literature | Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012. | |||||
529-0431-00L | Physical Chemistry III: Molecular Quantum Mechanics ![]() | O | 4 credits | 4G | B. H. Meier, M. Ernst | |
Abstract | Postulates of quantum mechanics, operator algebra, Schrödinger's equation, state functions and expectation values, matrix representation of operators, particle in a box, tunneling, harmonic oscillator, molecular vibrations, angular momentum and spin, generalised Pauli principle, perturbation theory, electronic structure of atoms and molecules, Born-Oppenheimer approximation. | |||||
Learning objective | This is an introductory course in quantum mechanics. The course starts with an overview of the fundamental concepts of quantum mechanics and introduces the mathematical formalism. The postulates and theorems of quantum mechanics are discussed in the context of experimental and numerical determination of physical quantities. The course develops the tools necessary for the understanding and calculation of elementary quantum phenomena in atoms and molecules. | |||||
Content | Postulates and theorems of quantum mechanics: operator algebra, Schrödinger's equation, state functions and expectation values. Linear motions: free particles, particle in a box, quantum mechanical tunneling, the harmonic oscillator and molecular vibrations. Angular momentum: electronic spin and orbital motion, molecular rotations. Electronic structure of atoms and molecules: the Pauli principle, angular momentum coupling, the Born-Oppenheimer approximation. Variational principle and perturbation theory. Discussion of bigger systems (solids, nano-structures). | |||||
Lecture notes | A script written in German will be distributed. The script is, however, no replacement for personal notes during the lecture and does not cover all aspects discussed. | |||||
529-0058-00L | Analytical Chemistry II | O | 3 credits | 3G | D. Günther, T. Bucheli, M.‑O. Ebert, P. Lienemann, G. Schwarz | |
Abstract | Enhanced knowledge about the elemental analysis and spectrocopical techniques with close relation to practical applications. This course is based on the knowledge from analytical chemistry I. Separation methods are included. | |||||
Learning objective | Use and applications of the elemental analysis and spectroscopical knowledge to solve relevant analytical problems. | |||||
Content | Combined application of spectroscopic methods for structure determination, and practical application of element analysis. More complex NMR methods: recording techniques, application of exchange phenomena, double resonance, spin-lattice relaxation, nuclear Overhauser effect, applications of experimental 2d and multipulse NMR spectroscopy, shift reagents. Application of chromatographic and electrophoretic separation methods: basics, working technique, quality assessment of a separation method, van-Deemter equation, gas chromatography, liquid chromatography (HPLC, ion chromatography, gel permeation, packing materials, gradient elution, retention index), electrophoresis, electroosmotic flow, zone electrophoresis, capillary electrophoresis, isoelectrical focussing, electrochromatography, 2d gel electrophoresis, SDS-PAGE, field flow fractionation, enhanced knowledge in atomic absorption spectroscopy, atomic emission spectroscopy, X-ray fluorescence spectroscopy, ICP-OES, ICP-MS. | |||||
Lecture notes | Script will be available | |||||
Literature | Literature will be within the script. | |||||
Prerequisites / Notice | Exercises for spectra interpretation are part of the lecture. In addition the lecture 529-0289-00 "Instrumentalanalyse organischer Verbindungen" (4th semester) is recommended. Prerequisite: 529-0051-00 "Analytische Chemie I" (3rd semester) | |||||
529-0625-00L | Chemical Engineering | O | 3 credits | 3G | W. J. Stark | |
Abstract | Chemical Engineering provides an introduction to production and process design. Beyond different types and operation of chemical or bio-reactors, issues of scaling, new synthesis methods and problems of industrial production are addressed. An introduction in heterogeneous catalysis and transport of impulse, mass and energy connect the new concepts to the basic education in chemistry and biology. | |||||
Learning objective | Intended for chemists, chemical engineers, biochemists and biologists, the course Chemical and Bioengineering 4th semester addresses the basics of production and process design. Starting with different reactors, process steps and unit operations in production, the industrial scale usage of chemicals and reagents are discussed and further illustrated by examples. Material and energy balances and the concept of selectivity are used to broaden the students view on the complexity of production and show how modern engineering can contribute to an environmentally sustainable production. In the second part of the lecture, reactors, single cells or living matter are discussed in terms of transport properties. Beyond metabolism or chemical processes, transport of impulse, mass and energy heavily influence chemical and biological processes. They are introduced simultaneously and provide a basis for the understanding of flow, diffusion and heat transport. Dimensionless numbers are used to implement transport properties in unit operations and process design. An introduction to heterogeneous catalysis connects the acquired concepts to chemistry and biology and shows how powerful new processes arise from combining molecular understanding and transport. | |||||
Content | Elements of chemical transformations: preparation of reactants, reaction process, product work-up and recycling, product purification; continuous, semibatch and batch processes; material balances: chemical reactors and separation processes, multiple systems and multistage systems; energy balances: chemical reactors and separation processes, enthalpy changes, coupled material and energy balances; multiple reactions: optimisation of reactor performance, yield and selectivity; mass transport and chemical reaction: mixing effects in homogeneous and heterogeneous systems, diffusion and reaction in porous materials; heat exchange and chemical reaction: adiabatic reactors, optimum operating conditions for exothermic and endothermic equilibrium reactions, thermal runaway, reactor size and scale up. | |||||
Lecture notes | Supporting material to the course is available on the homepage www.fml.ethz.ch | |||||
Literature | Literature and text books are announced at the beginning of the course. | |||||
402-0084-00L | Physics II | O | 4 credits | 3V + 1U | G. Dissertori | |
Abstract | This course is an introduction to classical physics, with special focus on applications in medicine. | |||||
Learning objective | Obtain an understanding of basic concepts in classical physics and their application (using mathematical pre-knowledge) to the solution of simple problems, including certain applications in medicine. Obtain an understanding of relevant quantities and of orders of magnitude. | |||||
Content | Electromagnetism; Thermodynamics; Optics. | |||||
Lecture notes | Will be distributed at the start of the semester. | |||||
Literature | "Physik für Mediziner, Biologen, Pharmazeuten", von Alfred Trautwein, Uwe Kreibig, Jürgen Hüttermann; De Gruyter Verlag. | |||||
Prerequisites / Notice | Voraussetzung Mathematik I+II (Studiengänge Gesundheitswissenschaften und Technologie bzw. Humanmedizin) / Mathematik-Lehrveranstaltungen des Basisjahres (Studiengänge Chemie, Chemieingenieurwissenschaften bzw. Interdisziplinäre Naturwissenschaften) | |||||
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Number | Title | Type | ECTS | Hours | Lecturers | |
529-0054-00L | Physical and Analytical Chemistry | O | 10 credits | 15P | E. C. Meister, R. Zenobi, M. Badertscher, M.‑O. Ebert, B. Hattendorf, Y. Yamakoshi | |
Abstract | Practical introduction to important experimental methods in physical and analytical chemistry. | |||||
Learning objective | The students have to carry out selected experiments in physical chemistry and evaluate measurement data. They acquire a good knowledge about the most important practical techniques in analytical chemistry. Laboratory reports have to be written to each experiment. | |||||
Content | Physical chemistry part: Short recapitulation of statistics and analysis of measurement data. Writing experimental reports with regard to publication of scientific works. Basic physical chemistry experiments (a maximum of six experiments form the following themes): 1. Phase diagrams (liquid-vapour and solid-liquid phase diagrams, cryoscopy); 2. electrochemistry and electronics; 3. quantum chemistry studies; 4. kinetics; 5. thermochemistry; 6. speed of sound in gases and liquids; 7. surface tension. Analytical chemistry part: 1. Introduction to the concept of sampling, quantitative elemental analysis and trace analysis, atomic spectroscopic methods, comparative measurements with electrochemical methods; 2. Separation methods, their principles and optimisation: comparison of the different chromatographic methods, effect of the stationary and mobile phases, common errors/artefacts, liquid chromatography, gas chromatography (injection methods). 3. Spectroscopic methods in organic structure determination: recording of IR and UV/VIS spectra, recording technique in NMR Mandatory exercises in spectroscopy in an accompanying tutorial 529-0289-00 "Instrumentalanalyse organischer Verbindungen" are an integral part of this course. | |||||
Lecture notes | Descriptions for experiments available online. | |||||
Literature | Für PC-Teil: Erich Meister, Grundpraktikum Physikalische Cheme, 2. Aufl. Vdf UTB, Zürich 2012. | |||||
Prerequisites / Notice | Prerequisites: 529-0051-00 "Analytische Chemie I (3. Semester)" 529-0058-00 "Analytische Chemie II (4. Semester)" in parallel to the lab class, or completed in an earlier semester. The course 529-0289-00L "Instumentalanalyse organischer Verbindungen" is an obligatory component of the lab class / praktikum. | |||||
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Number | Title | Type | ECTS | Hours | Lecturers | |
529-0131-00L | Inorganic Chemistry IV: (Nano-)Materials; Synthesis, Properties and Surface Chemistry | O | 4 credits | 3G | C. Copéret, A. Comas Vives | |
Abstract | Introduction into Solid State Chemistry, to the synthesis and properties of solids and to Nanomaterials. | |||||
Learning objective | Introduction into solid compounds and nanomaterials: syntheses, properties and applications. | |||||
Content | Section 1. Generalities – Prof. C. Copéret How do we apprehend a solid? Bulk vs. Surface Texture, Surface area (N2 adsorption, BET), Crystallinity (X-ray diffraction), Surface functionalities (IR, NMR), Acidity/Basicity (Probe molecules: pyridine, CO, CO2…), Point of Zero Electric Charge Section 2. Materials – Prof. C. Copéret 2.1 Synthetic methods 2.2 Sol-Gel and Solution Chemistry of Solids Section 3. Metal oxides – Prof. C. Copéret 3.1 Silica (SiO2) 3.2 Alumina (Al2O3) 3.3 Aluminosilicates (amorphous, layered materials and zeolites) 3.4. Mesostructured and hybrid materials 3.5 Semi-conducting and conducting oxides (e.g TiO2 and related materials, IrO2) 3.6 Other materials: Single and Complex Oxides, (MgO, CaO, MgAlO2, Perovskites), Polyoxometallates Section 4. Other materials Metal halides and chalcogenides Carbon-based materials Metals and Alloys Section 5. Bonding in Solids and Surfaces – Dr. Comas-Vives | |||||
Lecture notes | is provided on the internet. | |||||
Literature | A. West, Solid State Chemistry and its Applications, Wiley 1989; U. Müller, Anorganische Strukturchemie, Teubner Taschenbuch 2006; R. Nesper, H.-J. Muhr, Chimia 52 (1998) 571; C.N.R. Rao, A. Müller, A.K. Cheetham, Nanomaterials, Wiley-VCH 2007. | |||||
Prerequisites / Notice | AC-II | |||||
529-0232-00L | Organic Chemistry IV: Physical Organic Chemistry | O | 4 credits | 2V + 1U | P. Chen, R. Poranne | |
Abstract | Introduction to qualitative molecular orbital theory as applied to organic reactivity. Hückel theory, perturbation theory, molecular symmetry. Frontier orbital theory and stereoelectronic effects. Pericyclic reactions, photochemistry | |||||
Learning objective | Introduction to theoretical methods in organic chemistry | |||||
Content | Qualitative MO theory and its application to organic reactions, thermal rearrangements, pericyclic reactions. | |||||
529-0434-00L | Physical Chemistry V: Spectroscopy ![]() | O | 4 credits | 3G | R. Signorell | |
Abstract | Absorption and scattering of electromagnetic radiation; transition probabilities, rate equations; Einstein coefficients and lasers; selection rules and symmetry; band shape, energy transfer, and broadening mechanisms; atomic spectroscopy; molecular spectroscopy: vibration and rotation; spectroscopy of clusters, nanoparticles and condensed phases | |||||
Learning objective | The lecture is devoted to atomic, molecular, and condensed phase spectroscopy treating both theoretical and experimental aspects. The focus is on the interaction between electromagnetic radiation and matter. | |||||
Content | Absorption and scattering of electromagnetic radiation; transition probabilities, rate equations; Einstein coefficients and lasers; selection rules and symmetry; band shape, energy transfer, and broadening mechanisms; atomic spectroscopy; molecular spectroscopy: vibration and rotation; spectroscopy of clusters, nanoparticles and condensed phases | |||||
Lecture notes | is partly available | |||||
529-0580-00L | Safety, Environmental Aspects and Risk Management This course has been offered with a new title (before: Risk Analysis of Chemical Processes and Products) and by new lecturers (before Prof. Hungerbühler) since spring semester 2018. | O | 4 credits | 3G | S. Kiesewetter, K. Timmel | |
Abstract | Overview of the impact of industrial activities on the environment and human beings; required risk assessments and preventive measures as well as an insight on the fundamentals of Swiss legislation (environment / occupational safety). | |||||
Learning objective | Basic understanding of the impact of industrial activities on human beings and the environment; raise awareness for risks and safety concerns. | |||||
Content | Geschichtliche Aspekte der Ökotoxikologie / Erkenntnisse aus der Vergangenheit; Zusammenhänge Toxikologie-Ökotoxikologie; Risikoanalysen – wozu braucht es eine Risikoanalyse? Kennenlernen der Hilfsmittel zur Erarbeitung einer Risikoanalyse, Besprechung konkreter Beispiele; Einblick in die relevanten gesetzlichen Grundlagen (Schwerpunkt Schweizer Gesetzgebung) der Bereiche Umwelt und Arbeitssicherheit / Wie finde ich was ich suche? Wie finde ich mich in den Gesetztestexten zurecht? Hinweise zu weiteren nützlichen Hilfsmitteln zur Beurteilung der Auswirkungen auf Mensch und Umwelt; Aufbau einer Sicherheitsorganisation in einem Unternehmen, an einer Hochschule. | |||||
Lecture notes | Wird bei der ersten Vorlesung zur Verfügung gestellt. | |||||
Literature | Ergänzungsliteratur wird im Skript angegeben. | |||||
Prerequisites / Notice | Im Rahmen der Vorlesung wird eine Gruppenarbeit im Sinne eines Leistungselementes durchgeführt, die benotet wird. Die Schlussnote setzt sich wie folgt zusammen: Gruppenarbeit (Gewichtung 50%) und schriftlicher Prüfung (50%) Bei Wiederholung der schriftlichen Prüfung kann das Resultat der Gruppenarbeit aus einem früheren Semester übernommen werden. | |||||
![]() ![]() ![]() Students enrolled in the 6th semester of the Bachelor's programme in Chemistry at ETH are admitted to complete laboratory practicals and up to two research projects in the Master's elective/core subject areas. This applies solely to students with a maximum of 60 missing credits for the Bachelor's diploma. |
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